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Subject cui: C1442521|3082 Name: HGF|HGF gene Sem. type: gngm|gngm Novel: true

Predicate: STIMULATES

Object cui: 4233|8731|79811 Name: MET|RNMT|SLTM Sem. type: gngm|gngm|gngm Novel: true

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HGF|HGF gene STIMULATES MET|RNMT|SLTM Correct? #Y/N
Inactivation of MYO5B expression in gastric cancer cells expressing endogenous MYO5B inhibits HGF -stimulated MET degradation, concomitant with sustained c-MET levels and signaling. (PMID: 23456500) 0/0
Since HGF and EGF can activate STAT3 via gp130-independent MET and EGFR, respectively, we assumed that these factors account for STAT3-dependent liver regeneration. (PMID: 18068850) 0/0
In 1833 cells, human and mouse HGF increased Met and beta-catenin tyrosine phosphorylation and expression in nuclear and perinuclear compartments, beta-catenin nuclear translocation via Kank and TOPFLASH transactivation. (PMID: 20350802) 0/0
Knockdown of MYO5B expression in gastric cancer cells expressing endogenous MYO5B inhibits HGF -stimulated MET degradation, concomitant with sustained c-MET levels and signaling. (PMID: 23456500) 0/0
Interestingly, stimulation of the Met receptor by either GPCR agonists, EGF or its cognate ligand HGF, resulted in release of Met-associated beta-catenin and in its Met-dependent translocation into the nucleus, as analyzed by small interfering RNA-mediated knockdown of the Met receptor. (PMID: 15123705) 0/0
These events result from overexpression of c-met, leading to constitutive activation of Met signaling, despite the absence of the ligand SF/HGF. (PMID: 14665670) 0/0
HGF was found to induce c-MET activation and ERK activation, together with increased COX2 protein expression; (PMID: 23878598) 0/0
We demonstrate that MET activation by its ligand, HGF, also induces drug resistance, but through GAB1 signaling. (PMID: 20129249) 0/0
We demonstrate that c-Met activation by HGF leads to a survival cascade, whereas its blockade results in induction of mature B cell death. (PMID: 20639480) 0/0
Met activation by HGF induced degradation of the extracellular matrix and migration through matrigel coated transwells. (PMID: 17699048) 0/0
Co-expression of a kinase dead AXL blocked HGF activation of MET and indirectly AKT and p38MAPK. (PMID: 23648337) 0/0