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Subject cui: C0021701 Name: Integrins Sem. type: aapp Novel: true

Predicate: STIMULATES

Object cui: C1366537|998 Name: CDC42|CDC42 gene Sem. type: gngm|gngm Novel: true

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Integrins STIMULATES CDC42|CDC42 gene Correct? #Y/N
Dominant negative mutants of Rac and Cdc42 inhibit cell spreading in such a way as to suggest that integrins activate Cdc42 , which leads to the subsequent activation of Rac; (PMID: 9658176) 0/0
Activation of Rac and Cdc42 by integrins mediates cell spreading. (PMID: 9658176) 0/0
With the use of alpha(2)beta(1) integrin blocking antibody, we showed that collagen-induced Cdc42 activation was mediated by alpha(2)beta(1) integrin. (PMID: 18780290) 0/0