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Subject cui: C0960558 Name: 4-fluorofentanyl Sem. type: orch Novel: true


Object cui: 3763 Name: KCNJ6 Sem. type: gngm Novel: true

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4-fluorofentanyl STIMULATES KCNJ6 Correct? #Y/N
We demonstrate that p-fluorofentanyl more potently activates GIRK1/GIRK2 channels through opioid receptors than fentanyl and that the p-fluoro substitution also changes the potency profile from mu > kappa > delta (fentanyl) to mu > delta > or = kappa (p-fluorofentanyl). (PMID: 10945855) 0/0