At most 300 sentences shown!

Subject cui: C0666450|10188 Name: TNK2|ACK-2 Sem. type: gngm|aapp Novel: true

Predicate: STIMULATES

Object cui: C1366537|998 Name: CDC42|CDC42 gene Sem. type: gngm|gngm Novel: true

Sign in to evaluate.
TNK2|ACK-2 STIMULATES CDC42|CDC42 gene Correct? #Y/N
Like ACK-1, ACK-2 binds exclusively to activated (GTP-bound) Cdc42 and does not bind to its closest homologs, e.g. activated Rac. (PMID: 9312079) 0/0
ACK-2 could not be activated by addition of glutathione S-transferase (GST)-Cdc42 (Q61L), a GTPase-defective mutant, or by GTPgammaS-loaded GST-Cdc42 in in vitro kinase assays. (PMID: 9312079) 0/0
ACK-2 could not be activated by addition of glutathione S-transferase (GST)-Cdc42(Q61L), a GTPase-defective mutant, or by GTPgammaS-loaded GST-Cdc42 in in vitro kinase assays. (PMID: 9312079) 0/0