At most 300 sentences shown!

Subject cui: C1337109|331 Name: XIAP|BIRC4 gene Sem. type: gngm|gngm Novel: true

Predicate: INHIBITS

Object cui: C0220248|248|961|3375|84061 Name: ALPI|CD47|IAPP|MAGT1|CD47 Antigen Sem. type: gngm|gngm|gngm|gngm|aapp Novel: true

Sign in to evaluate.
XIAP|BIRC4 gene INHIBITS ALPI|CD47|IAPP|MAGT1|CD47 Antigen Correct? #Y/N
Apoptosis mediated by interleukin 1beta converting enzyme (ICE), which can be inhibited by Orgyia pseudotsugata nuclear polyhedrosis virus IAP (OpIAP) and cowpox virus crmA, was also inhibited by MIHA and MIHB. (PMID: 8643514) 0/0
OBJECTIVE: To localize the different proteins involved in the executioner step of apoptosis in the human testicular tissue: effector caspases (3, 6, and 7), caspase inhibitors called inhibitor of apoptosis proteins (IAPs, such as XIAP ), and IAP inhibitors such as Smac/DIABLO and to investigate XIAP and Smac expression and activation of caspase-3 in azoospermia. (PMID: 18177647) 0/0
In the present study, we examine the involvement of XIAP using a recently described synthetic IAP antagonist , AEG40730, and through comparison of a human XIAP-depleted tumour cell line with its isogenic wild-type control line. (PMID: 18851715) 0/0
These results show that XIAP is the critical discriminator between type I and type II apoptosis signalling and suggest that IAP inhibitors should be used with caution in cancer patients with underlying liver conditions. (PMID: 19626005) 0/0