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Subject cui: 4168 Name: MCF2 Sem. type: gngm Novel: true

Predicate: STIMULATES

Object cui: C1366537|998 Name: CDC42|CDC42 gene Sem. type: gngm|gngm Novel: true

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MCF2 STIMULATES CDC42|CDC42 gene Correct? #Y/N
Most of these contain a conserved catalytic domain, the DBL-homology (DH) domain , and activate Cdc42 or Rho but not Rac. (PMID: 7753201) 0/0
Surprisingly, we found that the PH domain was dispensable for guanine nucleotide exchange activity on Cdc42 in vitro, yet the PH domain enhanced the ability of the DH domain to activate Cdc42 signaling in vivo. (PMID: 12676355) 0/0
Role of the pleckstrin homology domain in intersectin-L Dbl homology domain activation of Cdc42 and signaling. (PMID: 12676355) 0/0