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Subject cui: C0001655|5443 Name: POMC|Corticotropin Sem. type: gngm|aapp Novel: true


Object cui: C0872265|5601 Name: MAPK9|SAPK Sem. type: gngm|aapp Novel: true

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POMC|Corticotropin STIMULATES MAPK9|SAPK Correct? #Y/N
Together these findings suggest that ACTH induces SAPK activity through a PKC and Ca+2-dependent pathway. (PMID: 9242678) 0/0
In contrast with the induction of SAPK by ACTH, ERK activity was inhibited in the adrenal cortex in vivo and in Y1 adrenal cells. (PMID: 9242678) 0/0
The isoquinolinesulfonamide inhibitors H-8 and H-89 blocked ACTH induction of SAPK activity at protein kinase C inhibitory doses but not at protein kinase A inhibitory doses. (PMID: 9242678) 0/0