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Subject cui: C0079419|7157 Name: TP53|TP53 gene Sem. type: gngm|gngm Novel: true


Object cui: C1368192|3845 Name: KRAS|KRAS2 gene Sem. type: gngm|gngm Novel: true

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TP53|TP53 gene STIMULATES KRAS|KRAS2 gene Correct? #Y/N
Activation of the proto-oncogene K-Ras and inactivation of the tumour suppressor gene loci INK4a, p53 and SMAD4 are characteristic for pancreatic cancer. (PMID: 12079267) 0/0
This includes mutational activation of the proto-oncogene Ki-ras and mutation/deletion of the p53 tumour suppressor gene. (PMID: 7828987) 0/0
Distinct genetic abnormalities (loss-of-function mutations of APC and p53 and oncogenic activation of Ki-ras) are associated with specific stages of the sporadic, most common types of colorectal tumors. (PMID: 9541486) 0/0