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Subject cui: 6416 Name: MAP2K4 Sem. type: gngm Novel: true

Predicate: STIMULATES

Object cui: C0872265|5601 Name: MAPK9|SAPK Sem. type: gngm|aapp Novel: true

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MAP2K4 STIMULATES MAPK9|SAPK Correct? #Y/N
SEK1 , which directly activates SAPK , is required for early embryonic development and has also been reported to be essential for normal lymphocyte development. (PMID: 9620683) 0/0
We find that MEKK regulates a new signalling cascade by phosphorylating an SAPK activator, SEK1 which in turn phosphorylates and activates SAPK . (PMID: 7997270) 0/0
The activity of SEK1/MKK4/JNKK , a MAPK kinase class protein kinase designated as a direct activator of JNK/SAPK , is also induced by MUK/DLK/ZPK or MST/MLK2 overexpression. (PMID: 9182538) 0/0