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Subject cui: C0061202 Name: Genistein Sem. type: bacs Novel: true

Predicate: INHIBITS

Object cui: 9469 Name: CHST3 Sem. type: gngm Novel: true

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Genistein INHIBITS CHST3 Correct? #Y/N
Moreover, genistein (1, 10 microM) significantly inhibited the 3beta-HSD -mRNA only in pregnenolone-stimulated granulosa cells. (PMID: 17728101) 0/0
Although both JAK2 and Stat5 were phosphorylated on tyrosine upon PRL treatment, the PRL mediated inhibition of 20alpha-HSD was not reversed by either tyrosine kinase inhibitors, AG18 and genistein, but was largely reversed by the protein synthesis inhibitor cycloheximide. (PMID: 9207201) 0/0
Genistein , 6-HF and cyanoketone, which is known as a typical 3beta-HSD inhibitor , were found to act as competitive inhibitors with K(i) values of 0.12 microM, 0.19 microM and 0.67 nM, respectively. (PMID: 15084349) 0/0