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Subject cui: C0003009 Name: Angiotensin II Sem. type: aapp Novel: true


Object cui: 185|472|9197 Name: AGTR1|ATM|SLC33A1 Sem. type: gngm|gngm|gngm Novel: true

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Angiotensin II STIMULATES AGTR1|ATM|SLC33A1 Correct? #Y/N
Expression of AT1A appears to be induced by angiotensin II in vascular smooth-muscle cells but is inhibited in the adrenal gland. (PMID: 8640285) 0/0
Furthermore, stimulation of AT1A by exogenous Ang II at a subpressor dose significantly exacerbated cardiac hypertrophy and dramatically augmented interstitial fibrosis in GC-A-KO mice but not in wild-type animals. (PMID: 12270869) 0/0
Although the activation of the rat AT1A receptor with AngII causes translocation of beta-arrestin2 to the receptor, no association of this molecule with the AT2 receptor can be detected after AngII treatment with confocal microscopy or bioluminescence resonance energy transfer. (PMID: 16359671) 0/0