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Subject cui: C0526768 Name: GE 2770 Sem. type: orch Novel: true

Predicate: INHIBITS

Object cui: C0300140|1915 Name: EEF1A1|EEF1A1 protein, human Sem. type: gngm|aapp Novel: true

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GE 2770 INHIBITS EEF1A1|EEF1A1 protein, human Correct? #Y/N
Two linear plasmids (pPR1, 27.5 kb, and pPR2, 16 kb) were identified in Planobispora rosea, an actinomycete that produces the antibiotic GE2270 , an inhibitor of the elongation factor Tu . (PMID: 9802023) 0/0
GE2270 A is active against Gram-positive microorganism and anaerobes and differs from the other EF-Tu inhibitors in its spectrum of antimicrobial activity. (PMID: 1908853) 0/0
Using a cell-free protein-synthesis system, we have established that the elongation factor (EF) Tu (EF-Tu) of the actinomycete Planobispora rosea, the producer of the thiazolyl peptide GE2270 , a specific EF-Tu inhibitor , is highly resistant to its own antibiotic, while it is completely inhibited by kirromycin, which is another inhibitor of this factor. (PMID: 8899707) 0/0