At most 300 sentences shown!

Subject cui: C0034809 Name: Glucocorticoid Receptor Sem. type: aapp Novel: true

Predicate: INHIBITS

Object cui: C0599933|5970|6857|64689|65125 Name: RELA|SYT1|GORASP1|WNK1|p65 Sem. type: gngm|gngm|gngm|gngm|aapp Novel: true

Sign in to evaluate.
Glucocorticoid Receptor INHIBITS RELA|SYT1|GORASP1|WNK1|p65 Correct? #Y/N
We also report that RU486 treatment of wild-type GR and DEX treatment of a transactivation mutant of GR each can significantly inhibit p65 activity. (PMID: 7823959) 0/0
While glucocorticoid receptors potently inhibited both p65 - and p65/Sp1-stimulated transcription, repression via mineralocorticoid receptors (MR) depended on the transcriptional activators that were present: p65-stimulated reporter activity was not repressed via MR, whereas a similar level of transcription resulting from synergistic activation by p65/Sp1-stimulation was repressed via MR. (PMID: 10718920) 0/0
In addition, we found that the zinc finger domain of GR is necessary for the inhibition of p65 . (PMID: 7823959) 0/0
In addition, we demonstrate that the ability of p65, p50, and c-rel subunits to bind DNA is inhibited by DEX and GR. (PMID: 7823959) 0/0