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Subject cui: C0031727 Name: Phosphotransferases Sem. type: aapp Novel: true

Predicate: STIMULATES

Object cui: C0872265|5601 Name: MAPK9|SAPK Sem. type: gngm|aapp Novel: true

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Phosphotransferases STIMULATES MAPK9|SAPK Correct? #Y/N
SPRK also activates cotransfected SEK-1/MKK-4, a dual specificity kinase which phosphorylates and activates SAPK . (PMID: 8702571) 0/0
MLKs activate JNK/SAPK in vivo by directly phosphorylating and activating the JNK kinase SEK-1 (MKK4 and -7). (PMID: 12738796) 0/0
Inhibition of p38MAP kinase potentiates the JNK/SAPK pathway and AP-1 activity in monocytic but not in macrophage or granulocytic differentiation of HL60 cells. (PMID: 11400164) 0/0
To study the mechanisms by which mitogen- and stress-activated protein kinases regulate cell cycle re-entry, we have used a panel of conditional kinases that stimulate defined MAPK or SAPK cascades. (PMID: 14981547) 0/0
The data demonstrate that SAPKs are subject to complex controls through both induction of SAPK expression and the regulation mediated by upstream elements within this pathway. (PMID: 9740025) 0/0
In contrast to p42MAPK, activation of JNK/SAPK in Xenopus oocyte extracts was induced by both the yeast Ste20 and Shk1 kinases, as well as by mammalian Pak1. (PMID: 7592806) 0/0
The leucine-zipper (LZ) and sterile-alpha motif (SAM) kinase (ZAK) belongs to the MAP kinase kinase kinase (MAP3K) when upon over-expression in mammalian cells activates the JNK/SAPK pathway. (PMID: 12220515) 0/0