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Subject cui: C0011777 Name: Dexamethasone Sem. type: phsu Novel: true

Predicate: INHIBITS

Object cui: 54541 Name: DDIT4 Sem. type: gngm Novel: true

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Dexamethasone INHIBITS DDIT4 Correct? #Y/N
REDD1 mRNA expression was repressed by dexamethasone (DEX) in FDLE and ATII, but induced by DEX in fibroblasts. (PMID: 19127203) 0/0
Inhibitor studies support repression of REDD1 mRNA by DEX in FDLE was mediated via glucocorticoid receptor and not by nongenomic effects of glucocorticoids via MAPK pathways. (PMID: 19127203) 0/0
Effects of testosterone on REDD1 mRNA levels occurred within 1 h, required the androgen receptor, were blocked by bicalutamide, and were due to inhibition of transcriptional activation of REDD1 by dexamethasone. (PMID: 20032058) 0/0