At most 300 sentences shown!

Subject cui: C0600334 Name: silybin Sem. type: orch Novel: true

Predicate: INHIBITS

Object cui: C1332712|960 Name: CD44|CD44 gene Sem. type: gngm|gngm Novel: true

Sign in to evaluate.
silybin INHIBITS CD44|CD44 gene Correct? #Y/N
Silibinin suppresses EGFR ligand-induced CD44 expression through inhibition of EGFR activity in breast cancer cells. (PMID: 22110198) 0/0
Silibinin suppresses CD44 expression in prostate cancer cells. (PMID: 19966941) 0/0
In PC-3M cells, silibinin dose-dependently inhibited CD44 promoter activity up to 87%, caused a 90% inhibition of total CD44 and 70% decrease in CD44v7-10 RNA, and at the protein level, decreased total CD44 at 100-200 muM dose and decreased CD44v7-10 after 3 days. (PMID: 19966941) 0/0