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Subject cui: C0079904 Name: NF-kappa B Sem. type: aapp Novel: true

Predicate: INHIBITS

Object cui: C0599933|5970|6857|64689|65125 Name: RELA|SYT1|GORASP1|WNK1|p65 Sem. type: gngm|gngm|gngm|gngm|aapp Novel: true

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NF-kappa B INHIBITS RELA|SYT1|GORASP1|WNK1|p65 Correct? #Y/N
Compared to untreated cells, treatment with BM-ca inhibited both the constitutively activated NF-kappaB and p38 MAPK pathways, as assessed by inhibition of both phospho-p65 and phospho-IkappaBalpha and phospho-p38, respectively, but not the unphosphorylated forms. (PMID: 19885551) 0/0
5F inhibited NF-kB by stabilizing its inhibitor IkBalpha, reducing the nuclear p65 and inhibiting NF-kB activity. (PMID: 22227815) 0/0
5F inhibited NF-kB by stabilizing its inhibitor IkBalpha, reducing the nuclear p65 and inhibiting NF-kB activity. (PMID: 22227815) 0/0
Moreover, ILG attenuated the LPS-induced DNA binding activity and the transcription activity of nuclear factor-kappa B (NF-kappaB), and this was associated with a decrease in inhibitory kappa B-alpha (IkappaB-alpha) phosphorylation and in the subsequent blocking of p65 and p50 protein translocations to the nucleus. (PMID: 18295200) 0/0
We report using human peripheral blood monocytes and Chinese hamster ovary cells transfected with CD14 cells that acute alcohol treatment in vitro exerts NF-kappaB inhibition by disrupting phosphorylation of p65 . (PMID: 17548605) 0/0