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Subject cui: C0004002|26503 Name: SLC17A5|Aspartate Transaminase Sem. type: gngm|aapp Novel: true

Predicate: STIMULATES

Object cui: 250|470|6590|10850|26033|27295|55226|80150 Name: ALPP|ATHS|SLPI|CCL27|ATRNL1|PDLIM3|NAT10|ASRGL1 Sem. type: gngm|gngm|gngm|gngm|gngm|gngm|gngm|gngm Novel: true

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SLC17A5|Aspartate Transaminase STIMULATES ALPP|ATHS|SLPI|CCL27|ATRNL1|PDLIM3|NAT10|ASRGL1 Correct? #Y/N
Biochemical parameters like the AST and ALT were not affected, but significant increase in ALP and uric acid levels, at 2g/kg, was detected. (PMID: 17628367) 0/0
From the results of the related indicators of liver function and cholestasis, AEPM did not change the contents of ALT and AST in serum, but high dose of AEPM can increase the contents of ALP , GGT and TBA in serum (P < 0.05, P < 0.01) and decrease the content of TBIL in serum (P < 0.05). (PMID: 22860459) 0/0
Results: In the first month, the increase of ALP at all doses and the increase of AST at 200 mg/kg was significant, compared to the control group (p<0.05). (PMID: 24579678) 0/0
UDCA withdrawal resulted in a significant deterioration in liver biochemistry (increase of ALP of 75.6 %; p<0.0001; GGT of 117.9%, p<0.0001; bilirubin of 50.0%, p<0.001; ALT of 63.9%, p<0.005 and AST of 45.0%, p<0.005) and increase of Mayo Risk Score for PSC (change from baseline of + 0.5 point; p<0.003). (PMID: 24519384) 0/0