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Subject cui: C1448177|7124 Name: TNF|TNF protein, human Sem. type: gngm|aapp Novel: true

Predicate: INHIBITS

Object cui: C1332712|960 Name: CD44|CD44 gene Sem. type: gngm|gngm Novel: true

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TNF|TNF protein, human INHIBITS CD44|CD44 gene Correct? #Y/N
The membrane receptors integrin alpha1beta1 and CD44 were strongly inhibited by IL-1beta+TNF-alpha, while this inhibition was then recovered by PRP in collagen coating condition. (PMID: 21616530) 0/0
IL-1beta furthermore upregulated the expression of the integrin subunits alpha1, alpha2 and the adhesion molecule CD44 while the latter was downregulated by TNF-alpha. (PMID: 12898248) 0/0
Specific inhibitors of TNF-alpha and IL-1 specific inhibitors also abolished the sonophoresis-induced expression of HA, HAS3 and CD44 . (PMID: 19886962) 0/0