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Subject cui: C0079281|1906 Name: EDN1|Endothelin-1 Sem. type: gngm|aapp Novel: true

Predicate: STIMULATES

Object cui: C1366537|998 Name: CDC42|CDC42 gene Sem. type: gngm|gngm Novel: true

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EDN1|Endothelin-1 STIMULATES CDC42|CDC42 gene Correct? #Y/N
Herein, we show that G(salpha) stimulation by cholera toxin increased Cdc42 activation by endothelin-1 (ET-1), whereas pertussis toxin had no effect. (PMID: 16740995) 0/0
H-89, a protein kinase A (PKA) inhibitor, strongly inhibited Cdc42 activation by ET-1. (PMID: 16740995) 0/0
These results demonstrate that beta1Pix, along with PKA, plays a crucial role in the regulation of Cdc42 activation by ET-1. (PMID: 16740995) 0/0