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Subject cui: C0666743 Name: infliximab Sem. type: aapp Novel: true

Predicate: INHIBITS

Object cui: C0006560|1401 Name: CRP|C-reactive protein Sem. type: gngm|aapp Novel: true

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infliximab INHIBITS CRP|C-reactive protein Correct? #Y/N
The present study aimed: (i) to exclude a linkage disequilibrium (LD) between the two genes and (ii) to study the association between CRP polymorphisms and the response to infliximab , particularly the decrease in CRP after treatment, in Crohn's disease patients. (PMID: 16344720) 0/0
The initial corticosteroid dose, the number and frequency of apheresis sessions, or the previous failure of thiopurines and/or infliximab did not influence the initial remission rate, but a greater decrease in CRP levels was associated with a higher probability to obtain initial remission. (PMID: 22105230) 0/0
RESULTS: CRP was elevated in 36% of patients at baseline, and was significantly reduced by infliximab by week 2. (PMID: 21086905) 0/0